In multiple sclerosis, pathological changes of both tissue iron and myelin occur, yet these factors have not been characterized in a longitudinal fashion using the novel iron- and myelin-sensitive quantitative susceptibility mapping (QSM) MRI technique.We investigated disease-relevant tissue changes associated with myelin loss and iron accumulation
Immune checkpoint inhibitors have revolutionized cancer treatment by enhancing anti-tumor immune responses.However, their impact on fertility is an emerging concern, particularly among young patients, including children.This review aims to assess the effects of immune checkpoint inhibitors on reproductive health and fertility preservation strategie
The objective of the present study was to investigate the effects of a sustained-release multi-trace element ruminal bolus on sex ratio, the reproductive performance and lambs growth of Afshari ewes.Eighty Afshari cycling ewes during breeding season were used in the trial.The animals were synchronized using CIDR for 14 days and assigned into 4 grou
Anorectal malformation (ARM) is the absence of a functioning anus with an abnormal attachment of the anus or rectum with urinary or female genital systems in alpha phi blanket a newborn child.It is considered a birth defect and is associated with comorbidities that may affect the baby from the early stages of life.We report a case of an eight-month
Thymidine kinase 1 (TK1) phosphorylates thymidine nucleosides to generate thymidine monophosphate.This reaction belongs to the pyrimidine salvage route that is phylogenetically conserved.In the model plant Arabidopsis thaliana, TK activity contributes to maintain nuclear and organellar genome integrity by providing deoxythymidine-triphosphate (dTTP